Intermediate

6-broMo-2-(Methylthio)pyrido[2,3-d]pyriMidin-7(8H)-one

6-Bromo-7-chloro-2-(methylsulfanyl)pyrido[2,3-d]pyrimidine

8-Chloronaphthalene-1-carboxaldehyde

Deucravacitinib

3-Pyridazinecarboxylic acid, 4,6-dichloro-, lithium salt, hydrate (1:1:1)

2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline

(3R,4S)-4-ethyl-1,3-Pyrrolidinedicarboxylic acid 1-(phenylmethyl) ester

(3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester

N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic acid 1,1-dimethylethyl ester

N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic acid ethyl ester

4-(PYRIDIN-2-YL)AMINOCARBONYLPHENYLBORONIC ACID

(S)-benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate

(S)-benzyl 2-(8-amino-1-(4-(pyridin-2-ylcarbamoyl)phenyl)imidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate

(S)-4-(8-Amino-3-pyrrolidin-2-yl-imidazo[1,5-a]pyrazin-1-yl)-N- pyridin-2-yl-benzamide

ACP196, Acalabrutinib

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